March 26 reported that British and American scientists have recently developed a new drug that can help the immune system to suppress the growth of malignant tumors, or treat 7 cancers. Although this drug is only successfully tested in mice, scientists hope to extend it to clinical treatment of human cancer within two years.
The efficacy of the new drug is mainly directed against a large number of CD47 proteins that spread across the surface of cancer cells. The "credit" of this protein is to prevent cancer cells from being overwhelmed or swallowed by human immune macrophages. The newly-developed antibody drugs can block the "don't eat me signal" issued by CD47, which makes it possible for the body's immune system to drive directly into attacking tumor cells. This is what researchers have been dreaming of for decades. One of the researchers, Dr. Irving Weissman of Stanford University School of Medicine, said: "We implanted tumors from humans and tested them in mice. The results prove that this drug is The interception of my signal's success can inhibit the growth of tumors in mice, make them smaller, some of them even disappear, and have minimal toxic side effects." Successful cases include breast, intestinal and prostate tumors. Ovarian tumors, brain tumors, bladder tumors and liver tumors.
Researchers said that if clinical trials prove that the drug is effective for cancer patients, it could develop a new type of cancer therapy.
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