Cyclodextrin and its derivatives can be organic small molecule inclusion into the hydrophobic cavity, change of small organic molecules dissolved in water, but also through the electrical environment charge effect of the molecule, the reaction can be carried out under mild conditions, but also can realize the organic reaction in aqueous solution.
Although the unmodified cyclodextrins can improve the water solubility of organic molecules through the role of subject and object can be reactant inclusion into the cavity of the catalytic reaction, but due to the unmodified cyclodextrins in organic solvents, poor solubility and limited hydrophobic regions and catalytic activity, the cyclodextrin is limited in the application. So the cyclodextrin was chemically modified to compensate for the lack of cyclodextrins by modification of cyclodextrin, cyclodextrin can increase the main functional groups of species and quantity, improve the catalytic activity of organic reactions catalyzed by cyclodextrins, expand the scope of application of organic synthesis reactions catalyzed by cyclodextrins. The catalytic loop dextrin and its derivatives in organic reactions sometimes is not only to provide a cavity to accelerate the reaction speed, and the modified cyclodextrin can play a catalytic effect. In addition, cyclodextrin Derivatives can also be used as metal ligands to catalyze organic reactions with transition metals
Scientific Research Special Cyclodextrin Reagent mainly including Oligo Beta Cyclodextrin, Mono-6-Azido-6-Deoxy Beta Cyclodextrin, Mono Hexamethylenediamine Beta Cyclodextrin, Mono-6-Ethanediamine-6-Deoxy Beta Cyclodextrin, Mono-6-p-Toluenesulfonyl Beta Cyclodextrin, Polyethylene Polyamine Modified Beta Cyclodextri,mono azido beta cyclodextrin cas 98169-85-8,Oligo Beta Cyclodextrin cas 98169-85-8.
Oligo (lactic acid) -beta-cyclodextrin (OLA-B-CD) is a new cyclodextrin derivative. Oligo-(lactic acid) group that can be degraded in the human body modified cyclodextrin with the general characteristics of common cyclodextrin derivatives, also has unique properties: 1, excellent biocompatibility. 2, excellent controlled release of specific guest molecular. 3, adjustable water-solubility. 4, capability to form duel interactions with specific drugs [1].
OLA-β-CD can be used to improve the solubility of water insoluble drugs, enhance drug stability and bioavailability, and achieve controlled release system or delayed release system of drugs. OLA-β-CD is of immense value in the field of drug development.
Features and use of Mono-6-Ethanediamine-6-Deoxy Beta Cyclodextrin:
Organic amine groups in a neutral or acid conditions can be positively charged which have very good composite ability to guest molecules.
Diamine group can form complex with many metal ions , such as Cu2+,Cr3+,Mg2+ and so on. This provide new approachs to achieve artifical enzyme and highlight supramolecular researches.
Diamine also provide a secondary amine group and a primary amine group which can be linked to many functional group. This make diamine cyclodextrin an important intermediate for cyclodextrin synthsis.
Scientific Research Special Cyclodextrin Reagent
Mono Azido Deoxy Beta Cyclodextrin,Polyethylene Polyamine Modified Beta Cyclodextrin, Mono Toluenesulfonyl Beta Cyclodextrin, Mono Ethanediamine Deoxy Beta Cyclodextrin
Zhiyuan Biotchnology , http://www.zycydextrin.com